Help Find A Cure For ALS!


The Angel Fund for ALS Research (Angel Fund, Inc.) is an independent non-profit charity (04-3478977) dedicated to supporting ALS (Lou Gehrig’s Disease) investigations at UMass Chan Medical School in Worcester, MA, internationally recognized for its ground-breaking work in the fight against this devastating illness.

The Angel Fund is special.

We are not a national charity – we are local. We have very low overhead and administrative costs.

Why are they so passionate?

Because most have lived through the heartbreak of seeing their loved one live with ALS and lose their battle to this horrific disease.

100 Innings of Baseball 20th Anniversary Documentary

We’re kicking off the 20th-anniversary celebration with a bang! Alex B. Koppelman has filmed a must-see documentary that dives deep into the heart and soul of this iconic event. This documantary will allow viewers to relive two decades of unforgettable moments. Check out the trailer.

Our mission is to support ALS (Lou Gehrig’s Disease) research and scientific investigations at UMass Chan Medical School by raising funds through events, campaigns, foundation grants and numerous other community outreach activities, to aid in finding a cause, treatment and cure for ALS.

Our Non-Profit Setup

Our offices are located in the law firm of Nigro Pettipet and Lucas, courtesy of Directors Jan and Eugene Nigro. Angel Fund President Rich Kennedy and the board members are not paid. As a result, it means we have very low overhead and administrative costs so more money goes to research. We are proud to say that 92% of funds expended goes to research.

  • No rent
  • No utility bills
  • No high paid executives

Motor neuron toxin associated with ALS identified by UMass Chan investigators

An inorganic polyphosphate that contributes to death of motor neurons presents ‘entirely new perspective’

An international team of investigators has discovered that an inorganic polyphosphate released by nerve cells known as astrocytes in people with amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) contributes to the motor neuron death that is the signature of these diseases. The research, by Brigitte van Zundert, PhD, adjunct professor of neurology at UMass Chan and professor at the Universidad Andres Bello in Chile; Robert H. Brown Jr., DPhil, MD, professor of neurology, and colleagues appeared in Neuron.


Latest News Entries

January 9, 2022

ALS Research Update

Brief Summary and Research Update August 1, 2022 ALS Program – UMass Chan Medical School By Dr. Robert H. Brown, Jr. Over the last several months, ALS investigations at UMass Chan Medical School have had excellent momentum.  Collaborating with Prof. Paul Greer in the Program in Molecular Medicine at UMass, Dr. Brown has further characterized […]

December 28, 2021

Groundbreaking News for ALS Research

Pilot human study shows novel treatment suppresses mutant ALS gene The Angel Fund for ALS Research provides major funding (Wakefield, MA) – A clinical trial funded by The Angel Fund for ALS Research has shown significant progress in suppressing expression of the most commonly mutated ALS gene, C9ORF72 (C9). The C9 gene mutation, a lengthy […]

Our Partners

Angel Fund supporters make a difference in fighting ALS, and you can be one of them.